Dynamic insulin sensitivity index: importance in diabetes
نویسندگان
چکیده
منابع مشابه
Dynamic insulin sensitivity index: importance in diabetes.
The classical minimal model (MM) index of insulin sensitivity, S(I), does not account for how fast or slow insulin action takes place. In a recent work, we proposed a new dynamic insulin sensitivity index, S(I)(D), which is able to take into account the dynamics of insulin action as well. The new index is a function of two MM parameters, namely S(I) and p(2), the latter parameter governing the ...
متن کاملInsulin sensitivity in diabetes mellitus.
While the invention of insulin has brought an epoch-making pro gress in the treatment of diabetes mellitus,1) insulin resistance in this disease is reported to be on the increase. Accordingly, there is much literature in which classification of diabetes mellitus has been tried from insulin sensitivity.2) Falta and his associates have done a great deal in this line; for ex ample, insulin toleran...
متن کاملQuantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.
Insulin resistance plays an important role in the pathophysiology of diabetes and is associated with obesity and other cardiovascular risk factors. The "gold standard" glucose clamp and minimal model analysis are two established methods for determining insulin sensitivity in vivo, but neither is easily implemented in large studies. Thus, it is of interest to develop a simple, accurate method fo...
متن کاملDo glycemic index, glycemic load, and fiber play a role in insulin sensitivity, disposition index, and type 2 diabetes?
In this issue of Diabetes Care, Liese et al. (1) report on the relation of dietary glycemic index, glycemic load, carbohydrate, and fiber intake to measures of insulin sensitivity, insulin secretion, and adiposity in the Insulin Resistance Atherosclerosis Study (IRAS). The evaluation was confined to those with normal or impaired glucose tolerance and did not include diabetic individuals. As the...
متن کاملSurrogate index for insulin sensitivity composed of factors not using glucose and insulin in Japanese patients with diabetes
INTRODUCTION The aim of the present study is to propose a novel index of insulin sensitivity instead of homeostasis model assessment of insulin resistance (HOMA-IR), which has a fundamental limitation of validity when applied to subjects with lower insulin secretions or high fasting plasma glucose (FPG) levels. MATERIALS AND METHODS A total of 25 apparently healthy subjects and 24 patient...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2010
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.90340.2008